Reversible cyanide inhibition of spinach (Spinacea oleracea L.) nitrate reductase and non-exchangeabilityin vitroof protein bound molybdenum and tungsten

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Studies by electron-paramagnetic-resonance spectroscopy of the molybdenum centre of spinach (Spinacia oleracea) nitrate reductase.

The molybdenum centre of spinach (Spinacia oleracea) nitrate reductase has been investigated by e.p.r. spectroscopy of molybdenum(V) in reduced forms of the enzyme. The resting enzyme gives no signals attributable to Mo(V). However, on reduction with NADH, Mo(V) signals appeared at relatively short reaction times but decreased again on prolonged exposure to excess of the substrate as the enzyme...

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Molybdenum and Nitrate Reductase

Numerous investigators have shown that nitrate nitrogen accumulates in higher plants (l-3) and fungi (2, 4) which are deficient in molybdenum. Other workers have shown that sulfur, zinc, and manganese deficiencies in higher plants may also result in a similar phenomenon (5). The free amino acids present in molybdenum-deficient plants are usually less than those in normal tissues, thus indicatin...

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Effect of molybdenum and tungsten on the reduction of nitrate in nitrate reductase, a DFT study

The molybdenum and tungsten active site model complexes, derived from the protein X-ray crystal structure of the first W-containing nitrate reductase isolated from Pyrobaculum aerophilum, were computed for nitrate reduction at the COSMO-B3LYP/SDDp//B3LYP/Lanl2DZ(p) energy level of density functional theory. The molybdenum containing active site model complex (Mo-Nar) has the largest activation ...

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Oxidation--reduction midpoint potentials of the flavin, haem and Mo-pterin centres in spinach (Spinacia oleracea L.) nitrate reductase.

Oxidation-reduction midpoint potentials have been determined for the flavin, cytochrome b557 and Mo-pterin prosthetic groups of spinach (Spinacia oleracea L.) assimilatory nitrate reductase using visible, c.d. and room-temperature e.p.r. potentiometric titrations. At pH 7 and 25 degrees C, the midpoint potential for the FAD/FADH2 couple was determined by c.d. potentiometry to be -280 +/- 10 mV ...

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Reconstitution in vitro of nitrate reductase from apoprotein of molybdenum-deficient spinach.

Hirasawa, E. & Suzuki, Y. (1975) Phytochemistry 14,99-101 McGowan, R. E. & Muir, R. M. (1971) Plant Physiol. 47, 644-648 Smith, T. A. (1974) Phytochemiktry 13,1075-1081 Smith, T. A. (1975) Phytochemistry 14,865-890 Smith, T. A. & Bickley, D. A. (1974) Phytochemistry 13, 2437-2443 Tabor, C. W. & Kellogg, P. D. (1970) J. Biol. Chem. 245, 54245433 Weaver, R. H. & Herbst, E. J. (1958) J. Biol. Chem...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1971

ISSN: 0014-5793

DOI: 10.1016/0014-5793(71)80396-4